Preparation "Bifosin": instructions for use, composition, description, analogues and reviews

Do you know what constitutes amedicine "Bifosin"? Instructions for use, price, testimonials and indications for taking the mentioned preparation will be described below. Also from the article you will learn about what features are inherent in this tool, whether it has side effects, analogues and contraindications.

Form of the preparation, its composition, description and packaging

In what forms does the Bifosin medication go on sale?

• Cream. Instructions for use say that the main substance of this drug is bifonazole. As additional components, macrogol 400, propylene glycol and macrogol 4000 are added to it. Colorless 1% cream for external use has a uniform structure and is produced in aluminum tubes packed in cardboard packs.
• White or light cream powder (maybe withgrayish shade) for external use. Its active element is bifonazole, and auxiliary substances are corn starch, zinc oxide and talc. On sale it comes in polyethylene jars.
• Lightly colored or colorless transparentsolution for external use. Its active ingredient is bifonazole. As for additional substances, they include macrogol 400. You can buy this form in bottles of dark glass (droppers).
• Spray "Bifosin". The instruction for use states that this drug is marketed as 1% transparent and colorless liquid for external use. Its active substance is bifonazole, and propylene glycol, macrogol and isopropanol are used as auxiliary elements. You can buy this form in polymer bottles equipped with a sprayer.

Features of the drug

What properties are inherent in all forms of the drugBifosin? Instruction for use reports that it is an antifungal agent. The main target of this medication are membrane components of such fungal cells as ergosterols.

Bifonazole, which is part of this drug,It can suppress the processes of ergosterol synthesis at two stages of its formation. As a result of functional and structural effects, the cell membranes of the fungal cell are damaged.

For which bacteria is Bifosin effective? Instructions for use states that this drug may adversely affect dermatophytes (has a fungicidal effect on trichophyton, epidermofiton and microsporum), as well as yeast-like and mold fungi (has fungistatic effect).

It should also be noted that the medication in question has no effect on enterococci.

The minimum amount of the drug that has an effective antifungal effect is 5 ng / ml.

The concentration of the drug in 20 ng / ml contributes to the fungicidal effect (against fungi of the genus Candida), and in lower doses - fungistatic effect.

Pharmacokinetics

Is the external drug "Bifosin" absorbed? Instructions for use (the price of the drug is presented below) indicates that the drug penetrates well into the skin layers. Its absorption is 0.6-0.9%. The concentration of bifonazol in the blood is not determined.

After applying the cream or other forms of the drug (after 6 hours), the percentage of bifonazole in the skin is many times higher than the minimum effective concentration for harmful effects on fungi.

The duration of the active substance in the skin is 36-72 hours. Displays the drug in 19-32 hours, depending on the density of the dermis.

Indications

In what cases is prescribed external drug "Bifosin"? Instructions for use, reviews of dermatologists report that this drug should be administered only by a narrow specialist.

As a rule, it is used to treat skin that has been affected by dermatophytes, mold and yeast-like fungi, these are:

• ringworm smooth skin;
• pityriasis versicolor;
• mycoses of hands and feet;
• skin candidiasis superficial;
• ringworm on the head (use only powder, solution or spray);
• erythrasma.

Contraindications

There are not many contraindications for this drug. These include:

• the period of breastfeeding;
• hypersensitivity to drug substances.

It should also be noted that with extreme caution, this medication is prescribed to babies under one year old and pregnant women in the first trimester.

Drug "Bifosin": instructions for use

The drug for external use should be used once a day, before bedtime.

A thin layer of cream, powder or solution is applied tothe affected area of ​​skin is well rubbed. As for the spray, it is sprayed in the amount that is sufficient to thoroughly moisturize the integument. Also, the drug is applied to the adjacent areas. What is the dosage?

To treat a skin area the size of a palm, use a strip of cream with a length of 0.5-1 centimeter or a few drops of the medicinal solution (about 3 ml).

In order to achieve a satisfactory therapeutic effect, treatment must be carried out continuously for the following periods:

• with erythrasma and pityriasis - 2 weeks;
• with mycoses of interdigital areas and feet - 3-4 weeks;
• with dermatomycosis of smooth skin - 2-3 weeks;
• with ringworm - 4 weeks;
• with candidiasis of the skin (surface) - 2-4 weeks.

After elimination of all mycosis symptoms, the drug continues to be used for prophylaxis, applying it once a day for two weeks.

Adverse Events

What are the side effects on the background?use of the drug "Bifosin"? Instructions for use states that this remedy may cause local reactions such as skin irritation, flushing, burning sensation, eczema, allergic reactions, vesicular rash, pruritus, maceration, allergic dermatitis and peeling.

These phenomena are reversible and disappear immediately after stopping treatment.

Cases of overdose

What symptoms of overdose occur when the drug is used improperly? Experts say that the low systemic absorption of this drug makes overdosing impossible.

Special Recommendations

In the absence of a therapeutic result, it is necessary to consult a doctor and undergo an additional examination. In accordance with the data analyzes carried out the adjustment of treatment.

Avoid contact with the external drug in the eyes and other mucous membranes.

The use of the drug in infants (up to one year) is possible only under the supervision of a pediatrician.

Cost and analogy

The price of this tool depends on its form.release and may vary in the range of 40-120 rubles. As for analogues, they include the following products: “Bifas”, “Mikospor”, “Bifonazol”, “Mifungar”, “Ekodaks”, “Dermazole”, “Amiklon”, “Travogen”, etc.

Reviews

Now you know what constitutesmedicine "Bifosin". Cream (instructions for use, price, reviews are described in this article), as well as other forms of this drug are often prescribed for fungal infections of the skin. Patients claim that this tool copes with the task. After a few days of treatment, fungal manifestations disappear completely.

Another advantage of this drug is its low cost.