The drug "Preductal". Instructions for use
The drug "Preductal" instructions for usecharacterizes as a remedy having an antianginal and anti-ischemic effect. The active ingredient of the drug is trimetazidine hydrochloride. Among the auxiliary - calcium hydrogen phosphate dihydrate, magnesium stearate, hypromellose, anhydrous colloidal silicon, povidone.
The composition of the envelope is as follows: E 171 (titanium dioxide), E 172 (red iron oxide), magnesium stearate, hypromellose, macrogol 6000, glycerol.
The drug "Preductal" comes in the form oftablets, characterized by a short period of validity. The active component of this agent stabilizes the energy metabolism of cells in the presence of hypoxia or ischemia in them. This is due to a decrease in the content of intracellular adenosine triphosphate.
The medicine "Preductal". Use in cardiology
In the course of clinical studies,that the considered pharmaceutical agent is expediently appointed or nominated both in complex, and in monotherapy. It is indicated for the treatment of not only chronic but also acute conditions.
Medication "Preductal" (instructions for useinforms) after getting into the digestive tract is absorbed quickly enough. The maximum concentration of the drug is reached after five hours. It is noted that the agent in question can be used regardless of the use of food. The half-life is approximately seven hours. In case the patient's age is more than sixty-five years, this period increases to twelve hours. Basically, the medication is excreted by the kidneys.
The administration of the drug "Preductal" recommends the application in the following cases:
- long-term treatment of coronary heart disease and prevention of an attack of angina pectoris (as part of mono- or complex therapy).
- elimination of noise in the ears, dizziness, hearing disorders and other symptoms of cochleovestibular failures of ischemic origin.
- therapy of chorioretinal vascular disorders with ischemic component.
The medication in question is assigned asrule, one tablet twice a day (preferably in the morning and evening hours). The duration of the therapeutic course is determined by a specialist individually.
As a result of the drug, nausea, vomiting (rarely), and allergic reactions may occur.
The drug "Preductal" (instructions for usecontains this information) is contraindicated in the presence of individual intolerance of its components, as well as during breastfeeding (if necessary, lactation should be suspended). It is also not prescribed during the waiting period for the child, because there are no clinical data on the safety of the drug at this time. In addition, for a similar reason, this medication should not be taken by patients suffering from impaired liver function, or to patients with severe renal failure.
As a result of treatment, the agent in questionalready on the fifteenth day in patients with angina pectoris increases coronary reserve, which prevents the occurrence of ischemic disruptions as a result of physical exertion. In addition, the number of attacks of angina is significantly reduced.
As a result of the application of the pharmaceutical agent in question, the development of digestive system disorders may occur.
The drug is recommended to store at an air temperature of not more than thirty degrees Celsius.
Shelf life of the drug is six months. After its expiration, the drug should not be used.
In pharmacies, the drug "Preductal" can be purchased only if a prescription is available.
