Means "Preductal". Indications for use

Tablets "Preductal" instruction describes as a drug that improves metabolism in the myocardium and neurosessory organs in ischemia. The active substance is trimetazidine hydrochloride.

Mechanism of action

"Preductal" remedy, indications for usewhich will be described below, promotes the normal functioning of ion channels in membranes. The medication also ensures the transport of sodium and potassium ions, maintenance of cell homeostasis. The drug reduces the size of the lesions of the myocardium, without having a direct effect on hemodynamic parameters. Against the background of angina, the drug helps to increase the coronary reserve, thus slowing the onset of ischemia, triggered by physical overstrain. The drug provides a limitation of fluctuations in blood pressure, without a significant change in the frequency of cardiac contractions. Patients with ischemic dysfunction with medication noted improvement in contractility in the left ventricle.

The drug "Preductal". Application. Price

The cost of medicine in pharmacies from 700 rubles. At what pathologies is the "Preductal" agent prescribed? Indications for the use of this medication are: IHD, cochlear-vestibular disorders of ischemic nature (tinnitus, dizziness and others). The drug is recommended for the prevention of angina attacks (in combination with other drugs or as a mono-drug). In chorioretinal vascular disorders with the ischemic component, the drug "Preductal" is also prescribed. Indications for use, the severity of the course of the pathology, as well as the patient's tolerance are the main criteria in determining the duration of the medication.

Dosing regimen

The drug is taken with food. It is advisable to take the medicine in the morning and evening hours. The recommended dose is 1 tablet. 2 p / day. The drug should not be chewed or crushed. The duration of therapy or prevention is established by the specialist personally.

Side effects

"Preductal" remedy, indications for usewhich are listed above, can provoke a number of complications. In particular, on the basis of therapy or prevention, abdominal pain, indigestion, constipation, vomiting and nausea are noted. In patients, asthenia, dizziness, tremors, and headaches may develop. To undesirable consequences carry various motor disturbances (reversible, as a rule, after discontinuation of reception), sleep disorder. A frequent side effect is an allergic reaction, manifested by a skin rash, irritation, urticaria. In some cases, Quincke's edema may occur. On the basis of medication, likely extrasystole, tachycardia, palpitations, orthostatic hypotension with dizziness, general weakness, loss of balance.

Contraindications

Do not prescribe medication to patients with renal diseaseinsufficiency, hypersensitivity, Parkinson's disease, motor disorders associated with the syndrome of "restless legs". It is not recommended for patients under 18 years old. The expediency of using the drug during pregnancy or during the period of feeding is determined by a specialist.